diff --git a/client/ayon_core/hooks/pre_remove_launcher_paths.py b/client/ayon_core/hooks/pre_remove_launcher_paths.py
new file mode 100644
index 0000000000..a96978b368
--- /dev/null
+++ b/client/ayon_core/hooks/pre_remove_launcher_paths.py
@@ -0,0 +1,36 @@
+""""Pre launch hook to remove launcher paths from the system."""
+import os
+from ayon_applications import PreLaunchHook, LaunchTypes
+
+
+class PreRemoveLauncherPaths(PreLaunchHook):
+    """Remove launcher paths from the system.
+
+    This hook is used to remove launcher paths from the system before launching
+    an application. It is used to ensure that the application is launched with
+    the correct environment variables. Especially for Windows, where
+    paths in `PATH` are used to load DLLs. This is important to avoid
+    conflicts with other applications that may have the same DLLs in their
+    paths.
+    """
+
+    order = 1
+
+    platforms = {"linux", "windows", "darwin"}
+    launch_types = {LaunchTypes.local}
+
+    def execute(self):
+        # Remove launcher paths from the system
+        paths = []
+        try:
+            ayon_root = self.launch_context.env["AYON_ROOT"]
+        except KeyError:
+            self.log.warning("AYON_ROOT not found in environment variables.")
+            return
+
+        paths.extend(
+            path
+            for path in self.launch_context.env.get("PATH", "").split(os.pathsep)
+            if not path.startswith(ayon_root)
+        )
+        self.launch_context.env["PATH"] = os.pathsep.join(paths)